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Cat. Number
IV0101
Chemical Name
IV0101 InVivoPro Anti-Mouse PD-L1(B7-H1, CD274) in vivo antibody, Clone 10F.9G2
Qty 1
5mg
Qty 2
50mg
Application Notes
99%
References

Catalog: IV0101

Cost advantage to: BE0101

Clone: 10F.9G2

Isotype: Rat IgG2b κ

Citations of the same Clone: 483

Product Details

CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes.

Specifications

CatalogIV0101
Product NameInVivoPro Anti-Mouse PD-L1(B7-H1, CD274) in vivo antibody, Clone 10F.9G2
Size1mg/5mg/25mg/50mg/100mg
IsotypeRat IgG2b κ
Clone10F.9G2
TargetPD-L1
Other NamesProgrammed cell death ligand 1,B7-H1,CD274,PD-L1
Isotype Control Catalog CodeIV0106 or Rat IgG2b Isotype Control 
Dilution BufferPBS, pH 7.2, contains no stabilizers or preservatives
ReactivityMouse
Host SpeciesRat
How much antibody to use in vivo200-500 μg per mouse; or 10 mg/kg. This range is based off the most recent publication data using the 10F.9G2 clone in vivo. Each investigator should  determine their own optimal working dilution for specific applications.
BackgroundCD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes.
ApplicationsIn vivo PD-L1 blocked
Purificationprotein A or G
StorageThis antibody is stable for at least 2 months when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C or -80°C. Avoid repeated freeze thaw cycles.
Shipping2-8°C with blue ice
ConcentrationLot specific, generally ≥ 5.0 mg/ml
Shelf Life12 months from the date of receipt if stored as recommended
FormulationPBS Buffer, PH 7.2, with no carrier protein, or preservatives.
Sterility0.2 μM filtered
Endotoxin≤ 1.0 EU/mg, by the LAL method
Purity99%

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