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/ Products Classification 点击展开+Cat. Number | GANT 58 |
Chemical Name | GANT 58 |
CAS Number | [64048-12-0] |
Mol. Formula | C24H16N4S |
Mol. Weight | 392.48 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2,3,4,5-Tetra(4-pyridyl)thiophene |
Solubility | Soluble to 25 mM in DMSO and to 25 mM in ethanol |
Storage condition | Store at +4°C |
References | GLI antagonist that inhibits GLI1-induced transcription (IC50 = 5 μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo. Purity: >99 % |
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