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Cat. Number
GANT 58
Chemical Name
GANT 58
CAS Number
[64048-12-0]
Mol. Formula
C24H16N4S
Mol. Weight
392.48
Qty 1
10mg
Qty 2
50mg
Synonym
2,3,4,5-Tetra(4-pyridyl)thiophene
Solubility
Soluble to 25 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at +4°C
References
GLI antagonist that inhibits GLI1-induced transcription (IC50 = 5 μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo.
Purity: >99 %
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