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Cat. Number
Ganaxolone
Chemical Name
Ganaxolone
CAS Number
[38398-32-2]
Mol. Formula
C22H36O2
Mol. Weight
332.53
Qty 1
10mg
Qty 2
50mg
Synonym
(3α,5α)-3-Hydroxy-3-methyl-pregnan-20 -one
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at +4°C
References
Potent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors (EC50 values are 94, 122 and 213 nM for α2β1γ2L, α3β1γ2L and α1β1γ2L receptors respectively). Exerts anticonvulsive effects in a broad range of animal seizure models.
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