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| Cat. Number | GANT 61 |
| Chemical Name | GANT 61 |
| CAS Number | [500579-04-4] |
| Mol. Formula | C27H35N5 |
| Mol. Weight | 429.61 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2 H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimeth ylbenzenamine |
| Solubility | Soluble to 50 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at -20°C |
| References | GLI antagonist that inhibits GLI1 and GLI2-induced transcription (IC50 ~ 5 μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo. Purity: >98 % |
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