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| Cat. Number | NU 6140 |
| Chemical Name | NU 6140 |
| CAS Number | [444723-13-1] |
| Mol. Formula | C23H30N6O2 |
| Mol. Weight | 422.52 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-[[6-(Cyclohexylmethoxy)-1H-purin- 2-yl]amino]-N,N-diethylbenzamide |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Desiccate at +4°C |
| References | Cyclin-dependent kinase 2 (cdk2) inhibitor; induces cell-cycle arrest at the G2-M phase. 10- to 36-fold more selective for cdk2-cyclin A over other cdks (IC50 = 0.41 μM for cdk2-cyclin A). Potentiates the apoptotic effect of Taxol (Cat. No. 1097) in HeLa cells; down-regulates the anti-apoptotic protein survivin. Purity: >99 % |
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