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Cat. Number
NU 2058
Chemical Name
NU 2058
CAS Number
[161058-83-9]
Mol. Formula
C12H17N5O
Mol. Weight
247.3
Qty 1
10mg
Qty 2
50mg
Synonym
6-(Cyclohexylmethoxy)-9H-purin-2-am ine
Solubility
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage condition
Store at +4°C
References
Cyclin-dependent kinase (cdk) 1 and cdk2 inhibitor (Ki values are 5 and 12 μM respectively). Inhibits growth of human tumor cells in vitro (mean GI50 = 13 μM). Also inhibits DNA topoisomerase II ATPase activity (IC50 = 300 μM).
Purity: >99 %
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