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| Cat. Number | NU 7026 |
| Chemical Name | NU 7026 |
| CAS Number | [154447-35-5] |
| Mol. Formula | C17H15NO3 |
| Mol. Weight | 281.31 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-(4-Morpholinyl)-4H-naphthol[1,2-b ]pyran-4-one |
| Solubility | Soluble to 10 mM in DMSO |
| Storage condition | Store at +4°C |
| References | ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC50 values are 0.23, 13.0, > 100 and > 100 μM for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair. Purity: >98 % |
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