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Cat. Number
PF 184
Chemical Name
PF 184
CAS Number
[1187460-81-6]
Mol. Formula
C32H32ClFN6O4
Mol. Weight
619.09
Qty 1
10mg
Synonym
8-[[[5-Chloro-2-[3,4-dimethyl-3,4-b is(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carb onyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz [g]indazole-3-carboxamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at +4°C
References
Potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress.
Purity: >98 %
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