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| Cat. Number | PF 3716556 |
| Chemical Name | PF 3716556 |
| CAS Number | [928774-43-0] |
| Mol. Formula | C22H26N4O3 |
| Mol. Weight | 394.47 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 8-[[(4R)-3,4-Dihydro-5-methyl-2H-1- benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dime thyl-imidazo[1,2-a]pyridine-6-carboxamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | H+,K+-ATPase inhibitor (pIC50 = 6 in human recombinant ion-leaky assays); more potent in acidic conditions. Highly selective for H+,K+-ATPase in vitro; displays no activity at Na+,K+-ATPase. Also displays selectivity for H+,K+-ATPase over a range of 50 receptors and ion channels (IC50 > 10 μM). Inhibits gastric acid secretion in rat and dog models. Purity: >98 % |
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