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| Cat. Number | PD 407824 |
| Chemical Name | PD 407824 |
| CAS Number | [622864-54-4] |
| Mol. Formula | C20H12N2O3 |
| Mol. Weight | 328.32 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Synonym | 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]ca rbazole-1,3(2H,6H)-dione |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Selective inhibitor of checkpoint kinases Chk1 and Wee1 (IC50 values are 47 and 97 nM respectively). Displays selectivity over a range of other protein kinases; IC50 values are 3.4, 3.75, > 5, > 50, > 50 and > 50 μM for PKC, CDK4, other CDKs, c-Src, PDGFR and FGFR respectively. Purity: >98 % |
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