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/ Products Classification 点击展开+Cat. Number | SB 612111 hydrochloride |
Chemical Name | SB 612111 hydrochloride |
CAS Number | [371980-98-2] |
Mol. Formula | C24H29Cl2NO.HCl |
Mol. Weight | 454.86 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 7-[[4-(2,6-Dichlorophenyl)-1-piperi dinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzo cyclohepten-5-ol hydrochloride |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at -20°C |
References | Selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). Antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. Potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model. Purity: >98 % |