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Cat. Number
SB 612111 hydrochloride
Chemical Name
SB 612111 hydrochloride
CAS Number
[371980-98-2]
Mol. Formula
C24H29Cl2NO.HCl
Mol. Weight
454.86
Qty 1
10mg
Qty 2
50mg
Synonym
7-[[4-(2,6-Dichlorophenyl)-1-piperi dinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzo cyclohepten-5-ol hydrochloride
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at -20°C
References
Selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). Antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. Potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model.
Purity: >98 %
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