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| Cat. Number | SB 525334 |
| Chemical Name | SB 525334 |
| CAS Number | [356559-20-1] |
| Mol. Formula | C21H21N5 |
| Mol. Weight | 343.42 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 6-[2-(1,1-Dimethylethyl)-5-(6-methy l-2-pyridinyl)-1H-imidazol-4-yl]quinoxaline |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl |
| Storage condition | Store at -20°C |
| References | Selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-β1-induced mRNA expression in kidney cells. Attenuates bleomycin-induced pulmonary fibrosis. Purity: >97 % |
下一个：SB 612111 hydrochloride上一个：SB 452533 |
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