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| Cat. Number | SB 657510 |
| Chemical Name | SB 657510 |
| CAS Number | [474960-44-6] |
| Mol. Formula | C19H22BrCIN2O5S |
| Mol. Weight | 505.81 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-Bromo-N-[4-chloro-3-[[(3R)-1-meth yl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzene sulfonamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at RT |
| References | Selective urotensin-II (UT) receptor antagonist (Ki values are 61, 17, 30, 65 and 56 nM at human, monkey, cat, rat and mouse receptors respectively). Inhibits U-II-induced intracellular Ca2+ mobilization (IC50 = 180 nM) and antagonizes the contractile action of U-II in isolated mammalian arteries and aortae (EC50 = 50 - 189 nM). Purity: >98 % |
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