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| Cat. Number | 733976903690003 |
| Chemical Name | 埃博霉素 Epothilone A |
| CAS Number | 152044-53-6 |
| Category | Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |
| Mol. Formula | C26H39NO6S |
| Mol. Weight | 493.66 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Synonym | (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; (-)-Epothilone A; Epothilone A; |
| Solubility | Soluble in DMSO (≥99mg/mL) and Ethanol (≥99mg/mL). Practically insoluble in Water (<1mg/mL). |
| References |
Bollag, D.M., et al.: Cancer. Res., 55, 2325 (1995), The epothilones are cytotoxic agents from the common soil bacteria Sorangium cellulosum. They have taxol like mechanism as microtubule stabilizers binding to beta tubulin. The cytotoxity of epothilone A is comparable to that of taxol. |
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