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/ Products Classification 点击展开+Cat. Number | 733976400777639 |
Chemical Name | 埃博霉素 Epothilone B |
CAS Number | 152044-54-7 |
Category | Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |
Mol. Formula | C27H41NO6S |
Mol. Weight | 507.68 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Appearance | White Powder |
Synonym | (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; (-)-Epothilone B; EPO 906; EPO 906A; Epothilone B; Patupilone; |
Melting Pt. | 95-97°C |
Solubility | Chloroform, Dichloromethane, DMSO, Ethanol, Methanol |
Storage condition | -20°C |
References |
Bollag, D.M., et al.: Cancer. Res., 55, 2325 (1995),
The epothilones are cytotoxic agents from the common soil bacteria Sorangium cellulosum. They have taxol like mechanism as microtubule stabilizers binding to beta tubulin. The cytotoxity of epothilone B was found to be superior than that of taxol. |
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