您的位置:首页>>分析化学>>脂类分析标准品>>1248 9(Z),11(Z)-十八碳二稀酸 9(Z),11(Z)-Octadecadienoic acid 544-70-7
Cat. Number
1248
Chemical Name
1248 9(Z),11(Z)-十八碳二稀酸 9(Z),11(Z)-Octadecadienoic acid 544-70-7
CAS Number
544-70-7
Mol. Formula
C18H32O2
Mol. Weight
280
Qty 1
25mg
Appearance
solid
Application Notes
96+% GC; TLC; identity confirmed by MS
Synonym
9-cis, 11-cis-CLA
Melting Pt.
40-42°C
Solubility
ethanol, methanol, chloroform, ethyl ether
Storage condition
-20°C
References

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9(Z),11(E)-十八碳二烯酸 9(Z),11(E)-Octadecadienoic acid 25mg

9(Z),11(E) - 十八碳二烯酸甲酯 Methyl 9(Z), 11(E)-octadecadienoate 25mg

9(E),11(E)-十八碳二烯酸 9(E),11(E)-Octadecadienoic acid 25mg

9(E),11(E)-十八碳二烯酸甲酯 Methyl 9(E),11(E)-octadecadienoate 25mg

9(Z),11(Z)-十八碳二稀酸 9(Z),11(Z)-Octadecadienoic acid 25mg

9(Z), 11(Z)十八碳二稀酸甲酯 Methyl 9(Z), 11(Z)-octadecadienoate 25mg

Application Notes:

9(Z),11(Z)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. Due to its being a minor component it is very helpful as a comparison to the major isomers 9(Z),11(E)-CLA and 10(E),12(Z)-CLA. 9(Z),11(Z)-CLA has been demonstrated to have a more potent antiproliferative effect than the more common 9(Z),11(E)-CLA isomer when incubated with human colon cancer cells.

References:
1. Helen B. MacDonald, Journal of the American College of Nutrition, Vol. 19, No. 90002, 111S-118S, 2000
2. Mairéad Coakley, Mark C. Johnson, Emma McGrath, Shafiqur Rahman, R. Paul Ross, Gerald F. Fitzgerald, Rosaleen Devery, Catherine Stanton, Nutrition and Cancer, 56(1) pp. 95-102, 2006


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