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| Cat. Number | 10-4542 |
| Chemical Name | 10-4542 N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide 1431612-23-5 |
| CAS Number | 1431612-23-5 |
| Mol. Formula | C33H43N7O2 |
| Mol. Weight | 569.74 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | White solid |
| Application Notes | 98% by TLC NMR (Conforms) |
| Synonym | N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide |
| Solubility | Soluble in DMSO (up to 10 mg/ml). |
| Storage condition | -20℃ |
| Stability | Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| References | UNC1999 (1431612-23-5) is an orally bioavailable, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50's = 45 nM and 2 nM respectively).1 Inhibition of EZH2 with UNC1999 enhanced the efficacy of gefitinib (Cat.# 10-1148) in suppressing the proliferation of colon cancer cells
References/Citations
UNC1999 ，货号10-4542 上海惠诚提供5mg 25mg UNC1999，美国focus原装进口，咨询电话021-60498804 |
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