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Cat. Number
H2041
Chemical Name
H2041 二氢神经酰胺 N-Octadecanoyl-D-erythro-dihydrosphingosine
Category
synthetic
Mol. Formula
C36H73NO3
Mol. Weight
568
Qty 1
10mg
Appearance
solid
Application Notes
98+% TLC
Synonym
N-C18:0-D-erythro-Dihydroceramide; N-Octadecanoyl-D-erythro-sphinganine; N-Stearoyl-D-erythro-dihydrosphingosine
Solubility
warm chloroform/methanol, 5:1; hot ethanol; DMSO
Storage condition
-20°C
References

1. Y. Mizutani, A. Kihara, and Y. Igarashi “Identifcation of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation” FEBS Letters, vol. 563 pp. 93-97, 2004
2. J. Soriano et al. “Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1” Progress in Lipid Research, Vol. 44 pp. 345-356, 2005
3. W. Zheng “Fenretinide increases dihydroceramide and dihydrosphingolipids due to inhibition of dihydroceramide desaturase” Georgia Institute of Technology, 2006
4. J. Idkowiak-Baldys et al. “Dihydroceramide Desaturase Activity is Modulated by Oxidative Stress” Biochem. J., Vol. 427(2) pp. 265-274, 2010
5. J. Stiban et al. “Dihydroceramide hinders ceramide channel formation: Implications on apoptosis” Apoptosis, Vol. 11(5) pp. 773-780, 2006
6. J. Kraveka et al. “Involvement Of The Dihydroceramide Desaturase In Cell Cycle Progression In Human Neuroblastoma Cells” Journal of Biological Chemistry., Vol. 282(23) pp. 16718-16728, 2007
下一个：N-十七酰基-D-赤式-鞘氨醇 N-Heptadecanoyl-D-erythro-sphingosine上一个：N-Acetyl-L-threo-sphingosine
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