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Cat. Number
H1829
Chemical Name
H1829 N-Acetyl-L-threo-sphingosine
Category
synthetic
Mol. Formula
C20H39NO3
Mol. Weight
342
Qty 1
1mg
Appearance
solid
Application Notes
98+% TLC, GC
Synonym
N-C2:0-L-threo-Ceramide
Solubility
chloroform, ethanol, DMSO, DMF (up to 5mg/ml)
Storage condition
-20°C
References

1. M. Ullman and N. Radin “The Enzymatic Formation of Sphingomyelin from Ceramide and Lecithin in Mouse Liver” The Journal of Biological Chemistry, vol. 249 pp. 1506-1512, 1974
2. K. Sandhoff et al. “Specificity of human glucosylceramide -glucosidase towards synthetic glucosylsphingolipids inserted into liposomes” European Journal of Biochemistry, vol. 160 pp. 527-535, 1986
3. K. Wong, X. Li, N. Hunchuk “N-Acetylsphingosine (C -ceramide) Inhibited Neutrophil Superoxide Formation and Calcium Influx” Journal of Biological Chemistry, Vol. 270 pp. 3056-3052, 1995
4. N. S. Radin, “Designing anticancer drugs via the achilles heel: ceramide, allylic ketones, and mitochondria” Bioorganic and Medicinal Chemistry, Vol. 11(10) pp. 2123-2142, 2003

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