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| Cat. Number | 066236814008890 |
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| Chemical Name | Adipogenesis Assay Kit |
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| References |
Background ReadingCamp, H.S., Ren, D., and Leff, T. Adipogenesis and fat- Spiegelman, B.M., and Flier, J.S. Adipogenesis and obesity: Rounding out the big picture. Cell 87 377-389 (1995). Tong, Q., and Hotamisligil, G.S. Molecular mechanisms of adipocyte differentation. Rev Endocr Metab Disord 2 349-355 (2001). Prusty, D., Park, B., Davis, K.E., et al. Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome proliferator- Scherer, P.E., Lisanti, M.P., Baldini, G., et al. Induction of caveolin during adipogenesis and association of GLUT4 with caveolin- Thompson, G.M., Trainor, D., Biswas, C., et al. A high- Vidal-Puig, A., Jimenez-Linan, M., Lowell, B.B., et al. Regulation of PPAR γ gene expression by nutrition and obesity in rodents. J Clin Invest 97 2553-2561 (1996). Show all 7 Hide all but first 3
Description
Obesity is a growing concern worldwide and has reached epidemic proportions in the United States.1 It is a risk factor in many major chronic diseases that afflict our society, including cardiovascular disease, diabetes mellitus, and cancer. In recent years, numerous studies have focused on identifying the mechanism of development of obesity, which is a process of either increasing the number of fat cells (fat cell hyperplasia) or enlargement of fat cells with each cell carrying greater amounts of fat (fat cell hypertrophy), or both.2,1 The ability to regulate the cell cycle and differentiation of adipocytes are key in the development and physiology of obesity and also in the origin of cancer. Understanding of these processes is critical to a rational approach to the treatment of obesity and cancer. Cayman’s Adipogenesis Assay Kit provides the reagents required for studying the induction and inhibition of adipogenesis in the established 3T3-
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Camp, H.S., Ren, D., and Leff, T. Adipogenesis and fat- 2 Spiegelman, B.M., and Flier, J.S. Adipogenesis and obesity: Rounding out the big picture. Cell 87 377-389 (1995). |
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