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| Cat. Number | 066126815540116 |
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| Chemical Name | DPP (IV) Inhibitor Screening Assay Kit |
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| References |
Background ReadingDurinx, C., Lambeir, A., Bosmans, E., et al. Molecular characterization of dipeptidyl peptidase activity in serum. Soluble CD26/dipeptidyl peptidase IV is responsible for the release of X- Mentlein, R. Dipeptidyl- Kikkawa, F., Kajiyama, H., Shibata, K., et al. Dipeptidyl peptidase IV in tumor progression. Biochim Biophys Acta 1751 45-51 (2005). Morimoto, C., Lord, C.I., Zhang, C., et al. Role of CD26/dipeptidyl peptidase IV in human immunodeficiency virus type 1 infection and apoptosis. Proc Natl Acad Sci USA 91 9960-9964 (1994). Fleischer, B. CD26: A surface protease involved in T- Heike, M., Möbius, U., Knuth, A., et al. Tissue distribution of the T cell activation antigen Ta1. Serological, immunohistochemical and biochemical investigations. Clin Exp Immunol 74 431-434 (1988). Lambeir, A., Pereira, J.F.D., Chacón, P., et al. A prediction of DPP IV/CD26 domain structure from a physico- Langley, A.K., Suffoletta, T.J., and Jennings, H.R. Dipeptidyl peptidase IV inhibitors and the incretin system in type 2 Diabetes Mellitus. Pharmacotherapy 27 1163-1180 (2007). Doupis, J., and Veves, A. DPP4 inhibitors: A new approach in diabetes treatment. Adv Ther 25(7) 627-643 (2008). Havre, P.A., Abe, M., Urasaki, Y., et al. The role of CD26/dipeptidyl peptidase IV in cancer. Front Biosci 13 1634-1645 (2008). Show all 10 Hide all but first 3
Description
DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-
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