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| Cat. Number | 287132840155739 |
| Chemical Name | AMD 3100 octahydrochloride |
| CAS Number | [155148-31-5] |
| Mol. Formula | C28H54N8.8HCl |
| Mol. Weight | 794.48 |
| Qty 1 |
10mg |
| Synonym | 1,1'-[1,4-Phenylenebis-(methylene)]- bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride |
| Solubility | Soluble to 100 mM in water |
| Storage condition | Desiccate at -20°C |
| References | Highly selective CXCR4 chemokine receptor antagonist (IC50 values are 0.02 - 0.13 and > 25 μM for CXCR4 and all other chemokine receptors respectively). Switches inflammatory responses from Th2 to Th1 type and reduces airway hyperresponsiveness in a mouse model of asthma. Potently inhibits HIV-1 and HIV-2 replication in vitro (EC50 = 4 - 35 nM) and mobilizes hematopoietic stem cells in vivo. |
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