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| Cat. Number | 286729694401909 |
| Chemical Name | AG 555 |
| CAS Number | [133550-34-2] |
| Mol. Formula | C19H18N2O3 |
| Mol. Weight | 322.36 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (E)-2-Cyano-3-(3,4-dihydroxyphenyl) -N-(3-phenylpropyl)-2-propenamide |
| Solubility | Soluble to 30 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 μM) that displays 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Induce G1 growth arrest selectively in transformed cells (IC50 values are 6.4 and 9.4 μM in HPV16-immortalized and normal keratinocytes respectively). Purity: >99 % |
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