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Cat. Number
286724417704872
Chemical Name
AG 494
CAS Number
[133550-35-3]
Mol. Formula
C16H12N2O3
Mol. Weight
280.28
Qty 1
10mg
Qty 2
50mg
Synonym
(E)-2-Cyano-3-(3,4-dihydroxyphenyl) -N-phenyl-2-propenamide
Solubility
Soluble to 5 mM in ethanol and to 50 mM in DMSO
Storage condition
Desiccate at +4°C
References
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively).
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