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| Cat. Number | 286136406099583 |
| Chemical Name | A 841720 |
| CAS Number | [869802-58-4] |
| Mol. Formula | C17H21N5OS |
| Mol. Weight | 343.45 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 9-(Dimethylamino)-3-(hexahydro-1H-a zepin-1-yl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4 (3H)-one |
| Solubility | Soluble to 50 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at RT |
| References | Potent, non-competitive mGlu1 receptor antagonist that displays 34-fold selectivity over mGlu5 (IC50 values are 10 and 342 nM respectively). Displays no significant activity at a range of other GPCRs, ion channels and transporters. Exhibits analgesic effects; decreases mechanical allodynia in models of neuropathic pain. Also impairs cognitive function. Purity: >98 % |
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