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/ Products Classification 点击展开+Cat. Number | 286071879203814 |
Chemical Name | A 438079 hydrochloride |
CAS Number | [899507-36-9] |
Mol. Formula | C13H9Cl2N5.HCl |
Mol. Weight | 342.61 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 3-[[5-(2,3-Dichlorophenyl)-1H-tetra zol-1-yl]methyl]pyridine hydrochloride |
Solubility | Soluble to 5 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at RT |
References | Competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 μM). Possesses antinociceptive activity in models of neuropathic pain in vivo. Purity: >98 % |