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| Cat. Number | 286066960484229 |
| Chemical Name | A 419259 trihydrochloride |
| CAS Number | [364042-47-7] |
| Mol. Formula | C29H34N6O.2HCl |
| Mol. Weight | 592.01 |
| Qty 1 |
10mg |
| Synonym | 7-[trans-4-(4-Methyl-1-piperazinyl) cyclohexyl]-5-(4-phenoxyphenyl)-7H-Pyrrolo[2,3-d]p yrimidin-4-amine trihydrochloride |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Inhibitor of Src family kinases (SFK) (IC50 = 0.1 - 0.3 μM). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Blocks Stat5 and Erk activation in vivo. Displays no inhibition of EGFR kinase activity in HNSCC cells. Purity: >98 % |
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