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Cat. Number
286066960484229
Chemical Name
A 419259 trihydrochloride
CAS Number
[364042-47-7]
Mol. Formula
C29H34N6O.2HCl
Mol. Weight
592.01
Qty 1
10mg
Synonym
7-[trans-4-(4-Methyl-1-piperazinyl) cyclohexyl]-5-(4-phenoxyphenyl)-7H-Pyrrolo[2,3-d]p yrimidin-4-amine trihydrochloride
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
Storage condition
Store at +4°C
References
Inhibitor of Src family kinases (SFK) (IC50 = 0.1 - 0.3 μM). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Blocks Stat5 and Erk activation in vivo. Displays no inhibition of EGFR kinase activity in HNSCC cells.
Purity: >98 %
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