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Cat. Number
284479898150709
Chemical Name
Bay 11-7821
CAS Number
[19542-67-7]
Mol. Formula
C10H9NO2S
Mol. Weight
207.25
Qty 1
10mg
Synonym
(2E)-3-[(4-Methylphenyl)sulfonyl]-2 -propenenitrile
Solubility
Soluble to 25 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at +4°C
References
Irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation (IC50 ~ 10 μM); leads to decreased NF-κB and subsequent decreased expression of adhesion molecules. Also reversibly activates MAP kinases and stimulates apoptosis.
Purity: >99 %
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