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| Cat. Number | 284476933058553 |
| Chemical Name | Bay 11-7085 |
| CAS Number | [196309-76-9] |
| Mol. Formula | C13H15NO2S |
| Mol. Weight | 249.33 |
| Qty 1 |
10mg |
| Synonym | (2E)-3-[[4-(1,1-Dimethylethyl)pheny l]sulfonyl]-2-propenenitrile |
| Solubility | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation (IC50 ~ 10 μM); leads to decreased NF-κB and subsequent decreased expression of adhesion molecules. Also reversibly activates MAP kinases and stimulates apoptosis. Anti-inflammatory in vivo. Purity: >99 % |
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