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| Cat. Number | 284426698301921 |
| Chemical Name | Banoxantrone dihydrochloride |
| CAS Number | [136470-65-0] |
| Mol. Formula | C22H28N4O6.2HCl |
| Mol. Weight | 517.4 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1,4-Bis[[2-(dimethyloxidoamino)ethy l]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride |
| Solubility | Soluble to 50 mM in water and to 25 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4. Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 νM). Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat. No. 4091) in a mouse tumor model. Purity: >98 % |
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