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Cat. Number
282476973370803
Chemical Name
CGK 733
CAS Number
[905973-89-9]
Mol. Formula
C23H18Cl3FN4O3S
Mol. Weight
555.84
Qty 1
10mg
Qty 2
50mg
Synonym
α-Phenyl-N-[2,2,2-trichloro-1-[[[(4- fluoro-3-nitrophenyl)amino]thioxomethyl]amino]ethy l]benzeneacetamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at +4°C
References
Originally defined as a selective inhibitor of ATR and ATM kinases that reverses senescence in human BJ and HMEC cells. Decreases p21CIP1 levels in senescent with no effect on p53 and Bcl-2 family members.
Purity: >98 %
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