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| Cat. Number | 282472681396347 |
| Chemical Name | CGH 2466 dihydrochloride |
| CAS Number | [252198-68-8] |
| Mol. Formula | C14H9N3SCl2.2HCl |
| Mol. Weight | 395.13 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-(3,4-Dichlorophenyl)-5-(4-pyridin yl)-2-thiazolamine dihydrochloride |
| Solubility | Soluble to 10 mM in DMSO and to 5 mM in ethanol |
| Storage condition | Desiccate at +4°C |
| References | Adenosine A1, A2B and A3 receptor antagonist (IC50 values are 19, 21, and 80 nM respectively). Also inhibits p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). Displays potent anti-inflammatory effects in vitro and in vivo. Potentially useful for asthma and chronic obstructive pulmonary disease (COPD) research. Purity: >99 % |
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