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Cat. Number
279626270299222
Chemical Name
DR 2313
CAS Number
[284028-90-6]
Mol. Formula
C8H10N2OS
Mol. Weight
182.24
Qty 1
1mg
Qty 2
50mg
Synonym
1,5,7,8-Tetrahydro-2-methyl-4H-thio pyrano[4,3-d]pyrimidin-4-one
Solubility
Soluble to 40 mM in water
Storage condition
Store at +4°C
References
Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro. Brain penetrant.
Purity: >99 %
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