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/ Products Classification 点击展开+Cat. Number | 279626270299222 |
Chemical Name | DR 2313 |
CAS Number | [284028-90-6] |
Mol. Formula | C8H10N2OS |
Mol. Weight | 182.24 |
Qty 1 |
1mg |
Qty 2 | 50mg |
Synonym | 1,5,7,8-Tetrahydro-2-methyl-4H-thio pyrano[4,3-d]pyrimidin-4-one |
Solubility | Soluble to 40 mM in water |
Storage condition | Store at +4°C |
References | Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro. Brain penetrant. Purity: >99 % |