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| Cat. Number | GSK 690693 |
| Chemical Name | GSK 690693 |
| CAS Number | [937174-76-0] |
| Mol. Formula | C21H27N7O3 |
| Mol. Weight | 425.48 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl) -1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[ 4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Store at -20°C |
| References |
ATP-competitive pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM for Akt1, 2 and 3 respectively). Also exhibits some inhibition for AMPK, PKA and PAK and PKC isoforms (IC50 < 100 nM). Displays antiproliferative and apoptotic effects in tumor cell lines. |
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