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Cat. Number
GSK 650394
Chemical Name
GSK 650394
CAS Number
[890842-28-1]
Mol. Formula
C25H22N2O2
Mol. Weight
382.45
Qty 1
10mg
Qty 2
50mg
Synonym
2-Cyclopentyl-4-(5-phenyl-1H-pyrrol o[2,3-b]pyridin-3-yl-benzoic acid
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 values are 62 and 103 nM for SGK1 and SGK2 respectively). Displays > 30-fold selectivity over Akt and other related kinases. Inhibits androgen-stimulated growth of LNCaP cells, a human prostate carcinoma cell line (IC50 ~ 1 μM).
Purity: >97 %
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