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/ Products Classification 点击展开+Cat. Number | GNTI dihydrochloride |
Chemical Name | GNTI dihydrochloride |
Mol. Formula | C27H29N5O3.2HCl |
Mol. Weight | 544.48 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 5'-Guanidinyl-17-(cyclopropylmethyl) -6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7-2',3'-indo lomorphinan dihydrochloride |
Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at -20°C |
References | Highly potent κ opioid receptor antagonist (Ki = 0.18 nM for human cloned κ receptors expressed in CHO cells). Displays 208- and 799-fold selectivity over μ and δ receptors respectively. Reduces feeding behavior in rats with a much higher potency (300-30,000-fold) and a shorter duration of action than nor-binaltorphimine (Cat.No. 0347). Purity: >98 % |