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/ Products Classification 点击展开+Cat. Number | HDS 029 |
Chemical Name | HDS 029 |
Mol. Formula | C17H11ClFN5O |
Mol. Weight | 355.76 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Synonym | N-(4-[(-3-Chloro-4-fluorophenyl)ami no]pyrido[3,4-d]pyrimidin-6-yl-2-butynamide |
Solubility | Soluble to 25 mM in DMSO |
Storage condition | Store at -20°C |
References | Potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively). Inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB autophosphorylation in MDA-MB-453 human breast carcinoma cells (IC50 values are 2.5 and 24 nM respectively). Purity: >97 % |
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