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/ Products Classification 点击展开+Cat. Number | HC 067047 |
Chemical Name | HC 067047 |
CAS Number | [883031-03-6] |
Mol. Formula | C26H28F3N3O2 |
Mol. Weight | 471.51 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2-Methyl-1-[3-(4-morpholinyl)propyl ]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrol e-3-carboxamide |
Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
Storage condition | Store at +4°C |
References | Potent and selective TRPV4 antagonist. Reversibly inhibits currents through mouse, human and rat TRPV4 orthologs (IC50 values are 17, 48 and 133 nM). Also inhibits the endogenous TRPV4-mediated response to 4α-PDH (IC50 = 22 nM). Selective for TRPV4 over TRPV1, TRPV2, TRPV3 and TRPM8 channels. Purity: >99 % |