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| Cat. Number | JNJ 10191584 maleate |
| Chemical Name | JNJ 10191584 maleate |
| CAS Number | [869497-75-6] |
| Mol. Formula | C13H15ClN4O.C4H4O4 |
| Mol. Weight | 394.81 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-[(5-Chloro-1H-benzimidazol-2-yl)c arbonyl]-4-methylpiperazine maleate |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo. Purity: >99 % |
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