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/ Products Classification 点击展开+Cat. Number | K 41498 |
Chemical Name | K 41498 |
CAS Number | [434938-41-7] |
Mol. Formula | C162H276N48O46 |
Mol. Weight | 3630.07 |
Qty 1 |
1mg |
Storage condition | Desiccate at -20°C |
References | Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. In rats in vivo, blocks urocortin-induced hypotension following systemic administration. |
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