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Cat. Number
K 41498
Chemical Name
K 41498
CAS Number
[434938-41-7]
Mol. Formula
C162H276N48O46
Mol. Weight
3630.07
Qty 1
1mg
Storage condition
Desiccate at -20°C
References
Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF, CRF and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF- and hCRF-expressing cells. In rats in vivo, blocks urocortin-induced hypotension following systemic administration.
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