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Cat. Number
Lyn peptide inhibitor
Chemical Name
Lyn peptide inhibitor
CAS Number
[222018-18-0]
Mol. Formula
C115H184N30O24
Mol. Weight
2370.91
Qty 1
1mg
Storage condition
Desiccate at -20°C
References
Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro. Inhibits airway eosinophilic inflammation in mouse model of asthma.
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