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Cat. Number
L-371,257
Chemical Name
L-371,257
CAS Number
[162042-44-6]
Mol. Formula
C28H33N3O6
Mol. Weight
507.59
Qty 1
10mg
Synonym
1-[4-[(1-Acetyl-4-piperidinyl)oxy]- 2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H) -yl)piperidine
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at RT
References
Potent, high affinity human oxytocin (OT) receptor antagonist (Ki = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V1a and V2. Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active.
Purity: >99 %
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