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Cat. Number
L-368,899 hydrochloride
Chemical Name
L-368,899 hydrochloride
CAS Number
[148927-60-0]
Mol. Formula
C26H42N4O5S2.HCl
Mol. Weight
591.23
Qty 1
1mg
Qty 2
10mg
Synonym
(2S)-2-Amino-N-[(1S,2S,4R)-7,7-dime thyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfony l]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfony l)butanamide
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
Storage condition
Store at +4°C
References
Potent, non-peptide and orally active oxytocin receptor antagonist (IC50 = 8.9 nM) that displays > 40-fold selectivity over vasopressin V1a and V2 receptors (IC50 values are 370 and 570 nM respectively). Antagonizes oxytocin-induced uterine contractions in vitro and in vivo.
Purity: >99 %
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