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Cat. Number
L-161,982
Chemical Name
L-161,982
CAS Number
[147776-06-5]
Mol. Formula
C32H29F3N4O4S2
Mol. Weight
654.72
Qty 1
10mg
Synonym
N-[[4'-[[3-Butyl-1,5-dihydro-5-oxo-1 -[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl ]methyl][1,1'-biphenyl]-2-yl]sulfonyl]-3-methyl-2-t hiophenecarboxamide
Solubility
Soluble to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
EP4 receptor antagonist that is selective over all other members of the prostanoid receptor family (Ki values are 0.024, 0.71, 1.90, 5.10, 5.63, 6.74, 19 and 23 μM for human EP4, TP, EP3, DP, FP, IP, EP1 and EP2 receptors respectively). Suppresses PGE2-induced bone formation in rats and prevents the nociceptive response induced by misoprostol in formalin-injected mice.
Purity: >99 %
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