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/ Products Classification 点击展开+Cat. Number | SB 202190 |
Chemical Name | SB 202190 |
CAS Number | [152121-30-7] |
Mol. Formula | C20H14N3OF |
Mol. Weight | 331.35 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-[4-(4-Fluorophenyl)-5-(4-pyridiny l)-1H-imidazol-2-yl]phenol |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at -20°C |
References | A highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms (IC50 = 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively). Also available as part of the MAPK Inhibitor Tocriset™. Purity: >99 % |