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| Cat. Number | NSC 95397 |
| Chemical Name | NSC 95397 |
| CAS Number | [93718-83-3] |
| Mol. Formula | C14H14O4S2 |
| Mol. Weight | 310.38 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2,3-bis[(2-Hydroxyethyl)thiol]-1,4- naphthoquinone |
| Solubility | Soluble to 50 mM in DMSO and to 5 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Potent and selective irreversible inhibitor of Cdc25 dual specificity phosphatases (Ki values are 32, 96 and 40 nM for inhibition of Cdc25A, -B and -C respectively). Displays 125 - 180-fold selectivity over VH1-related dual-specificity phosphatase and protein tyrosine phosphatase 1b. Inhibits carcinoma cell growth and blocks G2/M phase transition in vitro. Purity: >97 % |
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