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Cat. Number
NSC 87877
Chemical Name
NSC 87877
CAS Number
[56990-57-9]
Mol. Formula
C19H13N3O7S2
Mol. Weight
459.45
Qty 1
50mg
Synonym
8-Hydroxy-7-[(6-sulfo-2-naphthyl)az o]-5-quinolinesulfonic acid
Solubility
Soluble to 50 mM in water and to 100 mM in DMSO
Storage condition
Store at +4°C
References
Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μM for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Purity: >98 %
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