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Cat. Number
Org 20599
Chemical Name
Org 20599
CAS Number
[187652-71-7]
Mol. Formula
C25H40ClNO3
Mol. Weight
438.04
Qty 1
10mg
Qty 2
50mg
Synonym
(2β,3α,5α)-21-Chloro-3-hydroxy-2-(4-mo rpholinyl)pregnan-20-one
Solubility
Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
Storage condition
Store at RT
References
Positive allosteric modulator and at higher concentrations direct agonist of GABAA receptors (EC50 = 1.1 μM). Also displays positive modulation of glycine receptors (EC50 = 22.9 μM). Anesthetic steroid; induces hypnosis and loss of righting reflexes in mice.
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