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Cat. Number
Pyr3
Chemical Name
Pyr3
CAS Number
[1160514-60-2]
Mol. Formula
C16H11Cl3F3N3O3
Mol. Weight
456.63
Qty 1
10mg
Qty 2
50mg
Synonym
1-[4-[(2,3,3-Trichloro-1-oxo-2-prop en-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyraz ole-4-carboxylic acid
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at -20°C
References
Selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). Inhibits TRPC3-mediated Ca2+ influx (IC50 = 0.7 μM) and suppresses activation of nuclear factor of activated T cells (NFAT). Inhibits hypertrophic responses in cardiomyoctyes.
Purity: >98 %
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