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/ Products Classification 点击展开+Cat. Number | Pyr3 |
Chemical Name | Pyr3 |
CAS Number | [1160514-60-2] |
Mol. Formula | C16H11Cl3F3N3O3 |
Mol. Weight | 456.63 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 1-[4-[(2,3,3-Trichloro-1-oxo-2-prop en-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyraz ole-4-carboxylic acid |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at -20°C |
References | Selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). Inhibits TRPC3-mediated Ca2+ influx (IC50 = 0.7 μM) and suppresses activation of nuclear factor of activated T cells (NFAT). Inhibits hypertrophic responses in cardiomyoctyes. Purity: >98 % |
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