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| Cat. Number | PX 12 |
| Chemical Name | PX 12 |
| CAS Number | [141400-58-0] |
| Mol. Formula | C7H12N2S2 |
| Mol. Weight | 188.31 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-[(1-Methylpropyl)dithio]-1H-imida zole |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Competitive, irreversible thioredoxin-1 (Trx-1) inhibitor (Ki = 31 μM) that attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, ~10 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin polymerization in vitro and decreases tumor microvessel density in vivo. Purity: >99 % |
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